Detalhe da pesquisa
1.
Spartin-mediated lipid transfer facilitates lipid droplet turnover.
Proc Natl Acad Sci U S A
; 121(3): e2314093121, 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38190532
2.
Structural Basis for Regulation of Phosphoinositide Kinases and Their Involvement in Human Disease.
Mol Cell
; 71(5): 653-673, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30193094
3.
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis.
Proc Natl Acad Sci U S A
; 120(7): e2212909120, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36745811
4.
Molecular mechanisms of PI4K regulation and their involvement in viral replication.
Traffic
; 24(3): 131-145, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35579216
5.
Toxoplasma gondii mitochondrial association factor 1b interactome reveals novel binding partners including Ral GTPase accelerating protein α1.
J Biol Chem
; 300(1): 105582, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38141762
6.
Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11.
J Biol Chem
; 299(1): 102764, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36463963
7.
Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.
Proc Natl Acad Sci U S A
; 118(33)2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385319
8.
A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond.
J Biol Chem
; 298(10): 102439, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36049519
9.
In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate.
J Biol Chem
; 297(2): 100919, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34181950
10.
Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα.
J Am Chem Soc
; 144(14): 6326-6342, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353516
11.
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Nat Methods
; 16(7): 595-602, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31249422
12.
Investigating how intrinsically disordered regions contribute to protein function using HDX-MS.
Biochem Soc Trans
; 50(6): 1607-1617, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36454645
13.
Characterization of the c10orf76-PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication.
EMBO Rep
; 21(2): e48441, 2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31829496
14.
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature
; 538(7625): 402-405, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27732584
15.
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Nature
; 538(7625): 344-349, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27602946
16.
Conformational sampling of membranes by Akt controls its activation and inactivation.
Proc Natl Acad Sci U S A
; 115(17): E3940-E3949, 2018 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29632185
17.
Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA from Toxoplasma gondii.
Proc Natl Acad Sci U S A
; 115(45): E10548-E10555, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348763
18.
Dynamic structural biology at the protein membrane interface.
J Biol Chem
; 294(11): 3872-3880, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30692197
19.
The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme.
J Biol Chem
; 294(18): 7488-7502, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890560
20.
A single discrete Rab5-binding site in phosphoinositide 3-kinase ß is required for tumor cell invasion.
J Biol Chem
; 294(12): 4621-4633, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30659094